Introductory Biomedical Imaging

Ultrasound Imaging Simulations

Ultrasound Imaging Simulations

Ultrasound imaging is a medical analog of sound navigation and ranging (SONAR). Images are generated by directing a pulse of high-frequency (ultrasonic) sound into the body and detecting echoes that reflect or scatter from body interfaces and structures. The “echo time” between pulse creation and pulse detection is used to calculate object position. The echo amplitude is used to create image contrast, with strong echoes appearing white, weaker echoes as various shades of gray, and “absent” echoes as black. Doppler ultrasound further uses shifts in pulse frequency to measure object motion, such as blood flow. Doppler images are often color encoded and superimposed on grayscale structural ultrasound images. Ultrasound is extremely safe, relatively inexpensive, portable, and capable of creating excellent real-time images of soft tissues and organs. However, ultrasound is not well-suited to the study of air-filled cavities or structures encased in bone, like the brain. Premier applications include fetal imaging and Doppler ultrasound assessments of blood flow and heart valve movement.

The following simulations explore how ultrasound pulses are generated and detected, how pulse characteristics are used to create images, the factors that determine image quality (as quantified by resolution and contrast), and specialty imaging modes, including those used to monitor the eye, the heart, and blood flow. The simulations are listed in the recommended order of performance. Each simulation includes a home page from which the simulation can be run, together with links to simulation-specific Information, Background, and Activity documents.


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Measurement of Eye Dimensions Using 1D Echo Location

Explore the fundamentals of ultrasound imaging, including (a) pulse generation and detection by a transducer, (b) reflection and transmission of ultrasound pulses at tissue interfaces, (c) the impact of highly reflecting structures, (d) tissue depth determination from echo time, and (e) measurement of eye dimensions using amplitude (A) mode ultrasound imaging.

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Measurement of Fetal Heart Rate Using 1D Echo Location

Explore the fundamentals of one-dimensional motion (M) mode ultrasound imaging, including (a) measurement of fetal heart rate, (b) measurement of heart chamber size, and (c) effects of sampling frequency.

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Investigate 2D B-Mode Imaging

Explore the fundamentals of two-dimensional brightness (B) mode ultrasound imaging, including (a) mapping organ shape and depth, and (b) effects of transmission and changing reflector mismatch/reflectivity.

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Explore Lateral Resolution in Ultrasound

Explore the fundamentals of lateral (side-to-side) resolution in ultrasound imaging, including (a) the roles of beam width and lateral separation, (b) effects of ultrasound frequency, aperture size, beam focus, beam spread, and reflector depth, and (c) the interplay among ultrasound frequency, resolution, and penetration.

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Explore Axial Resolution in Ultrasound

Explore the fundamentals of axial (backward-forward) resolution in ultrasound imaging, including (a) roles of spatial pulse length (SPL) and axial separation, (b) effects of ultrasound frequency, and (c) the interplay among ultrasound frequency, resolution, and penetration.

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Explore Contrast in Ultrasound

Explore the fundamentals of contrast (gray scale variation) in ultrasound, including (a) effects of attenuation, ultrasound frequency, and mismatches in acoustic impedance on echo amplitude and image brightness, (b) the role of coupling gel, (c) acoustic shadowing, and (d) attenuation correction using time gain compensation (TGC).

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Explore Doppler Frequency Changes Arising from Observer (RBC) Motion

Explore the fundamentals of the Doppler effect, as a precursor to understanding its role in ultrasound imaging, including the effects of receiver motion and source motion on observed frequency.

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Introduction to Doppler Ultrasound

Explore the fundamentals of Doppler ultrasound, including (a) effects of flow speed, flow direction, Doppler angle, and transducer frequency on observed frequency shifts, (b) measurement of flow speed and direction from observed frequency shifts, and (c) color Doppler imaging.